B-402

Wilden Transfer Pump

Section B — Manufacturing Revision 0 3 pages

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1.0 Purpose 
 
 This document describes the standard operation of the diaphragm transfer pumps used in the
 liquids manufacturing department at Ion Labs. 
 
 2.0 Scope 
 
 This procedure applies to all diaphragm transfer pumps in operation at Ion Labs.
 
 3.0 Responsibility 
 
 3.1 It is the responsibility of operations personnel to follow this procedure.
 
 3.2 It is the responsibility of the department supervisor/manager to implement this
 
 procedure and ensure that the procedure is being followed. 
 
 4.0 Definitions 
 
 4.1 PPE -— Personal Protective Equipment 
 
 4.2 IPA-— Isopropyl! Alcohol 
 
 5.0 References 
 
 5.1 B-105, SOP, Preparation of Cleaning and Sanitizing Chemicals for Production and
 Warehouse 
 
 5.2 B-103, SOP, Small Parts Cleaning and General Sanitation 
 
 5.3 B-111, SOP, Cleaning of Manufacturing/Production Areas and Equipment
 
 6.0 Procedure 
 
 6.1 Operation 
 
 6.1.1 Protective eyewear is required when working with pneumatic equipment.
 
 
 

[SOP 

 Standard Operating Procedure SOP No | Rev 
 Wilden Transfer Pump B-402 0 Page 2 of 3 
 
 6.1.2 Ensure that the pump is equipped with a muffler. If the pump is not equipped
 
 with a muffler, then do not use the pump. 
 
 6.1.3 Before operation of transfer pumps in any batches ensure that it is clean. You
 must open up the pump and look inside the diaphragm to do this.
 
 6.1.4 Ensure that the pump is correctly assembled. 
 
 6.1.5 Attach a hose to the bottom of the pump — this is the suction side.
 
 6.1.6 Attach a hose to the top of the pump — this is the discharge side.
 
 6.1.7 Connect the pump to the discharge vessel. 
 
 6.1.8 Connect the pump to the feed vessel. 
 
 6.1.9 Attach the compressed air line with the air valve closed to the diaphragm pump.
 
 6.1.10 Open the valve slowly until the desired flow rate is achieved.
 
 6.2 Cleaning 
 
 6.2.1 Prepare a cleaning solution per SOP B-105 Preparation of Cleaning and
 
 Sanitizing Chemicals for Production and Warehouse. 
 
 6.2.2 This procedure follows the basic cleaning procedures listed in SOP B-111
 Cleaning of Manufacturing/Production Areas and Equipment. 
 
 6.2.3 Start by loosening all the manifold bolts with an appropriate wrench size.
 
 6.2.4 Remove the manifold bolts from the bottom seat by pushing them away from
 
 the pump body. 
 
 6.2.5 Remove the top and lower fluid manifolds. 
 
 6.2.6 Carefully set aside the ball check valve and seat. 
 
 6.2.7 Remove the liquid chamber plate (side plates) from the diaphragms.
 
 6.2.8 Wash any product residue that is evident in the top and bottom fluid channel
 with the prescribed cleaning solution. Use a pipe cleaner for residue inside the
 manifold. 
 
 6.2.9 Wash any product residue from the inside of the side plates with the prescribed
 cleaning solution. 
 
 

[SOP 

 Standard Operating Procedure SOP No Rev ae 
 Wilden Transfer Pump B-402 0 ge3o 
 
 6.2.10 Wash the same areas with water followed by a light spray of 70% IPA. Areas of
 
 spray indicated below. Allow to Air Dry. 
 
 6.2.11 Put the pump back together by: 
 
 6.2.11.1 Putting the liquid chamber plates (side plates) back on first.
 
 6.2.11.2 Putting the bottom and top back on with balls and seats in correct
 position with the shafts seated in place. 
 
 6.3 Sanitization Areas: 
 
 7.0 Revision History 

| Rev | Date | Description of Changes | CCR # | By |
|-----|----------|------------------------|-------|----|
| 0 | 08/09/21 | New procedure. N/A C. Rhoades | - | - |