Density Determination of Liquids

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1.0 Purpose 
 
 This procedure describes the steps for determining the density of liquid samples.
 
 2.0 Scope 
 
 This procedure is for determining the density of liquid samples, viscous liquid samples, and
 precious liquids that are small in volume. 
 
 3.0 Responsibility 
 
 3.1 ‘It is the responsibility of QC Analysts to follow this procedure.
 
 3.2 It is the responsibility of QC Laboratory Management to implement this procedure and
 
 to ensure that the procedure is being followed. 
 
 3.3. ‘It is the responsibility of QC Laboratory Management to keep this procedure aligned
 
 with current practices. 
 
 4.0 Definitions 
 
 4.1 Density — The mass per unit volume of a substance, most commonly described as g/mL
 
 4.2 QS -— Quantity Sufficient; refers to bringing the bottom of the meniscus of a liquid to
 the measuring line of the volumetric glassware 
 
 4.3 QC — Quality Control 
 
 
 

[SOP 

 Standard Operating Procedure SOP No | Rev 
 
 Density Determination of Liquids D-702 5 Page 2 of 4 
 
 5.0 References 
 
 5.1 D-702-F1, Form, Liquid Density Determination Test Ticket 
 
 52 C-501, SOP, Document Control Procedure 
 
 5.3 C-502, SOP, Record Storage, Retention, and Destruction 
 
 6.0 Procedure 
 
 6.1 Density determination of normal and viscous liquids 
 
 6.1.1 Depending on available quantity of liquid use a 10mL, 25mL, or a 50mL Class
 
 A volumetric flask. The greater the volume used, the greater the accuracy of the
 measurement. 
 
 6.1.1.1 Determine the temperature of the liquid being measured. If the density
 needs to be performed at a specific temperature preequilibrate the
 
 liquid and volumetric flask to the specified temperature before
 measuring. 
 
 6.1.1.2 Tare an appropriate volumetric flask on a calibrated analytical balance.
 
 QS the flask with the liquid sample and determine the weight.
 
 6.1.1.3 Take caution, especially when performing the density on viscous
 
 liquids to ensure no residue is on the walls of the volumetric flask
 above the volume line and this will add weight and provide an
 
 erroneous density value. 
 
 6.1.1.4 Also be sure to remove any bubbles that may be present in test
 
 solution. This can be performed by: 
 
 6.1.1.4.1 Putting the test liquid in a centrifuge before performing the
 
 test. 
 
 
 

[SOP 

 Standard Operating Procedure SOPNo | Rev 
 Density Determination of Liquids D-702 OO 
 
 6.1.1.4.2 Putting the test liquid before or after it has been added to a
 
 volumetric flask, to degas by sonication. If this is
 
 performed, be sure to allow sufficient time for the
 temperature of the liquid to reach equilibrium to negate any
 
 expansion of the liquid that has occurred. 
 
 6.1.1.5 Calculate the density with the following equation: 
 
 Density = (Totalwe- Flaskw:)/volume 
 
 6.1.1.6 Weight should be expressed in grams and volume expressed in
 
 milliliters unless otherwise specified. 
 
 6.1.1.7 Record the raw data, calculations, determined density along with the
 temperature of the liquid on the form D-702-F1. 
 
 6.2 Density determination of precious liquids 
 
 6.2.1 Determine the temperature of the precious liquid being measured. If the density
 
 needs to be performed at a specific temperature preequilibrate the liquid and
 volumetric flask to the specified temperature before measuring.
 
 6.2.2 Using a calibrated analytical balance tare a weigh boat. 
 
 6.2.3 Using a1 milliliter Class A pipette draw and weigh exactly 1mL of the precious
 
 liquid. 
 
 6.2.3.1 This process can be performed at any volume using a Class A pipette.
 
 6.2.4 Calculate the density with the following equation: 
 
 6.2.4.1 Density = Liquidw/Liquidvyor 
 
 6.2.5 Record the density along with the temperature of the liquid using Form
 D-702-F1 Liquid Density Determination Test Ticket. 
 
 
 

[SOP 

 Standard Operating Procedure SOP No Rev 
 Density Determination of Liquids D-702 Page 4 of 4 
 
 6.3 Documentation Requirements 
 
 6.3.1 All completed test tickets will be maintained as outlined in SOP C-501
 
 Document Control and SOP C-502 Record Storage, Retention, and Destruction.
 
 7.0 Revision History 

| Rev | Date | Description of Changes | CCR # | By |
|-----|----------|------------------------|-------|----|
| 0 | 05/06/10 | New - - | - | - |
| 1 | 02/25/13 | Updated SOP format. | 13-077 | B. Johns |

 Updated SOP format. Changed title. Combined procedure for 
 normal and viscous liquids. Corrected equation. Expanded 7 
 2 OheaS information on pipette verification and use of tips. Updated test Os 8. JeHas
 ticket. Biennial review 
 Biennial review: Eliminated use of variable pipettes. Incorporated
 2 Crh use of Class A, fixed volume pipettes. Changed responsibilities. ee E. Johns
 4 04/15/20 Scheduled review: Added specific techniques for viscous liquids CC-20-0299 | J. Maignan
 and removal of bubbles. 
 Added documentation requirements. Added additional SOP 
 5 09/21/23 | references. Revised test ticket to include logbook number. Updated | CC-23-0486 K. Burris
 format. Updated responsibilities section. 
 
 
 

[SOP 

 ION Liquid Density Determination Test Ticket 
 
 NLuatbrsi tional Form: D-702-F1 CCR No. CC-23-0486 Revision: 6 
 
 Logbook Number: 
 
 Balance ID #: Daily Calibration Verified: 
 
 R# Finished Product # 
 
 : i 
 Flask Weight (g): 
 
 Flask + Sample Weight (g): 
 
 Sample Volume (mL): 
 
 Sample Weight (g): 
 
 Sample Volume (mL): 
 
 Density Calculation: Liquid Mass(g)/ Liquid Volume(mL): 
 
 Density Specification (g/mL): 
 
 Temperature: Ion#: Cal Due: 
 
 Determination (circle one): Pass Fail 
 
 Comments: 
 
 Performed By/Date: 
 
 Reviewed By/Date: